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Fallout 76 Boss Killer builds

Builds for single-target burst against the toughest enemies. Bring one when the boss health bar is the only number that matters.

These builds are made with
Character Build Planner
Level 300+
s10
p4
e9
c9
i14
a3
l7
Revington Pain Train
Fallout 76 Pain Train/ChooChoo 4* build
AoE
Boss Killer
Close Range
Endgame
Melee
Published / Updated
byRev
Level 300+
s10
p9
e5
c7
i7
a10
l8
salt of the earth
Fallout 76 vats build
Boss Killer×2
Endgame×2
Glass Cannon×2
Meta×2
Published / Updated
byOU3THUMPER
Level 300+
s10
p11
e4
c2
i9
a9
l11
Commissioner Chaos -Solo-
Fallout 76 Salvaged Assaultron Beam build
Boss Killer
Close Range
Meta
Roleplay
Solo
Published / Updated
by@Metaphors

Become Commissioner Chaos as you ensure your TOTAL Victory across Appalachia with beams of glory.

Level 300+
s4
p10
e9
c11
i2
a10
l10
Kiing
Fallout 76 Heavy Weapons build
Long Range×2
Boss Killer
Endgame
Meta
Tank
Published / Updated
by@KingSlime
Level 300+
s10
p10
e11
c4
i1
a10
l10
Full Health - Ballistic
Fallout 76 build
Boss Killer×2
Close Range
Endgame
Long Range
Meta
Published / Updated
byGrizzle
Level 300+
s14
p10
e7
c4
i2
a9
l10
Ghoul Big Flame
Fallout 76 build
Boss Killer
Close Range
Endgame
Long Range
Tank
Published
byCountHollow
Level 300+
s9
p12
e10
c4
i5
a8
l8
5% health power armor heavy
Fallout 76 Bloodied Heavy power armor build
Boss Killer
Endgame
Meta
Published
by@YEETitsDATBOI
Level 300+
s9
p15
e2
c6
i5
a10
l9
Raging Ghoul
Fallout 76 Heavy-Gunner-Ghoul-Raid build
Boss Killer
Consumables
Endgame
Meta
Tank
Published / Updated
by@Bone
  • Use normal armor for stages 1/3/5
  • Only user Power armor for the 2nd/4th stage
  • Take the Herbivore serum a 2nd time to use carnivore buffs for 1 hour
  • Take Relish after Black-eyed so the XP bonus is not overridden
  • Use Gauss-Minigun to Build up Rage Stacks Quite Easy
  • Use toxic goo as needed
Level 300+
s8
p15
e4
c1
i7
a15
l6
Turtle's Raider Build
Fallout 76 Low Health Energy weapon build
Boss Killer
Close Range
Glass Cannon
Stealth
Published
by@GrimDesire

AngryTurtle's solo raid build for the first boss. Using the Quad Assaultron head charged to 20 and aimed for the Boss' shield, use VATs to crit. After one-tapping the shield you'll then swap to the Plasma Flamer and aim at the Boss' side. A little after reloading once you'll have killed the boss yourself.

Level 300+
s10
p10
e9
c3
i4
a10
l10
Uniques and other metas
Fallout 76 build
Boss Killer
Endgame
Solo
Tank
Team Player
Published / Updated
byPrometheus

Tried with new uniques (Red Terror, Bertha, Cold Shoulder, Lickety Split, Ace) Works amazing with all these guns!

Level 300+
s9
p13
e5
c3
i7
a10
l9
Low health human
Fallout 76 Endgame low health human commando build
Boss Killer
Endgame
Glass Cannon
Meta
Stealth
Published / Updated
byCaptnFnord¹⁶¹

Versatile low health build with weapon and armor options for damage, survival and tagging.

Level 300+
s8
p12
e7
c3
i8
a10
l8
Human bloodied power armor raid
Fallout 76 Human bloodied power armor raid build
Boss Killer
Endgame
Meta
Published / Updated
by@YEETitsDATBOI
Level 300+
s10
p10
e6
c4
i7
a14
l4
Heavy Energy Blood Sacrifice Tank
Fallout 76 Heavy Unlimited Vats build
Boss Killer
Endgame
Meta
Tank
Published
by@YEETitsDATBOI
Level 150+
s10
p10
e4
c3
i7
a10
l12
Mid lvl GMG Human
Fallout 76 build
Boss Killer
Meta
Tank
Published / Updated
byCaptnFnord¹⁶¹
Level 300+
s10
p8
e6
c4
i7
a8
l13
Heavy Gunner
Fallout 76 Big Guns build
Boss Killer
Endgame
Solo
Tank
Published / Updated
by@JustChasinIt
Level 300+
s10
p12
e6
c3
i5
a10
l10
Infinite Vats Minigun Low health
Fallout 76 build
Boss Killer×2
Tank×2
Close Range
Endgame
Published
byCaptnFnord¹⁶¹
Level 300+
s15
p7
e9
c10
i10
a1
l4
Ghoul Auto Axe build
Fallout 76 build
Boss Killer
Endgame
Melee
Tank
Published / Updated
byCaptnFnord¹⁶¹
Level 14
s1
p3
e1
c1
i1
a7
l6
BARE BONES ENO6 SHEILD
Fallout 76 build
Boss Killer
Solo
Published
by@poopman11

I use the Chinese Stealth Armor. For solo this works great as long as your not up in his face it will be in Caution, if you do get spotted retreat behind the pillars and wait.

Level 300+
s15
p4
e10
c4
i10
a1
l3
Feral Ghoul Pain Train
Fallout 76 build
Boss Killer
Melee
Tank
Published / Updated
byCaptnFnord¹⁶¹

This build uses various hidden buffs to optimize Pain Train damage, especially regarding the weapon. To get the best results, you should bring down the durability of the Gatling Plasma to 1%. Note: firing into the air to get bullet storm stacks does NOT cost any durability, just ammo. Notes on the armor: Vulcan is the BIS for this build, but any PA that can have Tesla Bracers will do (no Excav/Ultracite!)

Level 300+
s10
p12
e4
c3
i7
a10
l10
Ghoul GMG/TC
Fallout 76 Ghoul Endgame Gauss Minigun Teslacannon Power Armor VATScrit build
Boss Killer
Endgame
Meta
Tank
Published
byCaptnFnord¹⁶¹
Level 300+
s10
p7
e4
c5
i10
a10
l10
Shotghoul Daily Driver
Fallout 76 Do it all Shotgun Ghoul build
Boss Killer×2
Endgame×2
AoE
Close Range
Meta
Published
byPsychoSquire

This build can raid, can daily, can solo most stuff. And the cold shoulder makes the snake a breeze. Still need to use reflective PA or some trick for ENO but explosive cold shoulder will even hold drill with ease. Shotguns have finally come into their own! Thanks Todd!!

Level 300+
s7
p7
e2
c11
i10
a10
l9
West Tek Monster
Fallout 76 Archer XP Build build
AoE
Boss Killer
Endgame
Fast Leveling
Stealth
Published
byPsychoSquire

Who needs Nuka Grenades with Hat Trick?! Solely an XP Build, you would have to change up the armor to use this as a daily driver. But, it is possible if that is done. Added Daily armor on beneath the XP set.

Level 300+
s10
p10
e6
c4
i7
a9
l10
PA Gauss Mini
Fallout 76 build
Boss Killer
Endgame
Published / Updated
bykatie s
Level 300+
s5
p7
e8
c1
i10
a15
l10
Assaultron Head 100k dmg
Fallout 76 Reverse onslaught battleloaders ghoul build
Boss Killer
Close Range
Glass Cannon
Team Player
Published / Updated
byOkibum Matt

Build your crit meter with your cryolator and allow reverse onslaught stacks to build up. Once you reach 30 stacks, switch to the assaultron head, bash until you proc battleloaders, VATS crit on the weak point of your enemy, and watch it melt away. Repeat process as needed.

Level 300+
s15
p10
e7
c3
i1
a10
l10
PA Raid Ghoul
Fallout 76 build
Boss Killer
Endgame
Long Range
Tank
Published / Updated
byCountHollow