Skip to content
All Consumables

Psychobuff
Fallout 4 Consumable

Psychobuff

+25% Damage, +3 Strength, +3 Endurance and +65 max Health for 8 minutes.

15% 0.1
Chems

Psychobuff is a chem in Fallout 4. Its main effect: +25% Damage, +3 Strength, +3 Endurance and +65 max Health for 8 minutes. Each use carries a 15% chance of Psycho Addiction. It is made at the Chemistry Station.

2 perks change how well it works.

Used in Builds

Level 55
s.
p.
e.
c.
i.
a.
l.
CoA Inquisitor
Fallout 4 build
Level 44
s.
p.
e.
c.
i.
a.
l.
Explosive Meta
Everything blows up build

Jump into the character build planner with this consumable, plus the perks and items you've toggled, already selected, then build the rest of your loadout around it.

Create a build with Psychobuff

Stats and Effects

+25% Damage, +3 Strength, +3 Endurance and +65 max Health for 8 minutes.
Damage: x1.25 (8m)
Strength: +3 (8m)
Endurance: +3 (8m)
Max Health: +65 (8m)
Weight
0.1
Value
70

Effectiveness

These perks and items change what Psychobuff does. Toggle them and watch the effects above update. Scaled values show in yellow with their base alongside.
Perk
Chem Resistant

You gain complete immunity to chem addiction.

22
Perk
Chemist

Any chems you take now last an additional 200% longer.

16
32
45

Stacking

Taking another Psychobuff refreshes these buffs instead of stacking them; other Psycho-family items replace the buffs to the same stats.

Can Cause

Addiction (15% chance) (1)
Psycho Addiction
addiction

Psycho withdrawal. Lasts until a doctor, Addictol or a Refreshing Beverage cures it.

Strength -1

Physical Resistance -10

Crafting

Chemistry Station
1 ×Psycho
1 ×Buffout

More Consumables

Mentats
+2 Intelligence and +2 Perception for 5 minutes.
Chem
Mysterious Serum
Physical Resistance: +50 (1h), Strength: +5 (1h), Adds Fatigue & Suppresses Immunity (5s)
Chem
Orange Mentats
+5 Perception and +10% VATS Accuracy for 8 minutes. · VATS Hit Chance: x1.1 (8m)
Chem
Overdrive
+25% Damage and +25% Critical Chance for 8 minutes.
Chem
Psycho
+25% Damage and 25 Damage Resist for 5 minutes.
Chem
Psycho Jet
Slow Time, +25% Damage, +35 Damage Resist and +40 Max AP for 15 seconds.
Chem
Psychotats
+25% Damage, +15% Damage Resist and +3 Perception for 8 minutes.
Chem
Rad-X
+100 Rad Resist for 3 minutes
Chem
RadAway
Removes 300 Rads.
Chem
Railroad Stealth Boy
Detection by Movement: x0.5 (40s), Sneak: +50 (40s), Turns you mostly invisible. (40s)
Chem
Refreshing Beverage
Removes all Rads and cures addictions.
Chem
Resilient Sludge Cocktail
-150 Rad Resist and +75 Max Health for 12 minutes
Chem