Fallout 4 Boss Killer builds
Builds for single-target burst against the toughest enemies. Bring one when the boss health bar is the only number that matters.
A heavily armored Brotherhood Sentinel who combines military doctrine with advanced robotics and the power of Atom. Axiom fights from within modified T 60 power armor, supported by a custom Automatron and overwhelming heavy energy weapons, turning recovered technology into a force multiplier rather than a curiosity.
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Grab Spray n Pray from Cricket to start, as early as outside Diamond City
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Kiloton Radium Rifle is a guaranteed upgrade in Far Harbor
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Explosive Combat Shotgun is best, but requires luck or farming
If you get one or want to farm one you could take Rifleman instead, or just use an auto receiver
Don't shoot at your feet or you will blow up, too
Other crafting and qol passives are up to you
HP/Regen/Rad Regen recommended for Survival mode
Sneaky sniper who uses chems & nuka free to inflict maximum damage possible with semi-automatic rifle. Maximum efficiency at lowest level.
An all-around Commando focused on run-and-gun combat with automatic weapons and explosive damage. Uses the Spray n Pray and Explosive Combat Shotgun, while investing in settlement building, crafting, and general utility.